Ontology highlight
ABSTRACT:
SUBMITTER: Bardini G
PROVIDER: S-EPMC2887787 | biostudies-literature | 2010 May
REPOSITORIES: biostudies-literature
Bardini Gianluca G Giorda Carlo B CB Pontiroli Antonio E AE Le Grazie Cristina C Rotella Carlo M CM
Cardiovascular diabetology 20100521
<h4>Background</h4>The primary goal of therapy in patients with hypercholesterolemia and coronary heart disease (CHD) is reducing low-density lipoprotein cholesterol (LDL-C). This was a multicenter, randomized, double-blind, double-dummy study in patients with type 2 diabetes mellitus (T2DM).<h4>Methods</h4>Adult patients with T2DM and CHD (N = 93) on a stable dose of simvastatin 20 mg with LDL-C >or= 2.6 mmol/L (100 mg/dL) and <or= 4.1 mmol/L (160 mg/dL) were randomized to ezetimibe 10 mg plus ...[more]