Ontology highlight
ABSTRACT:
SUBMITTER: Lewis ZA
PROVIDER: S-EPMC2889519 | biostudies-literature | 2010 May
REPOSITORIES: biostudies-literature
Lewis Zachary A ZA Adhvaryu Keyur K KK Honda Shinji S Shiver Anthony L AL Selker Eric U EU
Proceedings of the National Academy of Sciences of the United States of America 20100419 18
Functionally distinct chromatin domains are delineated by distinct posttranslational modifications of histones, and in some organisms by differences in DNA methylation. Proper establishment and maintenance of chromatin domains is critical but not well understood. We previously demonstrated that heterochromatin in the filamentous fungus Neurospora crassa is marked by cytosine methylation directed by trimethylated Lysine 9 on histone H3 (H3K9me3). H3K9me3 is the product of the DIM-5 Lysine methylt ...[more]