Ontology highlight
ABSTRACT:
SUBMITTER: Hoebeek FE
PROVIDER: S-EPMC2889566 | biostudies-literature | 2010 May
REPOSITORIES: biostudies-literature
Hoebeek Freek E FE Witter Laurens L Ruigrok Tom J H TJ De Zeeuw Chris I CI
Proceedings of the National Academy of Sciences of the United States of America 20100415 18
The output of the cerebellar cortex is controlled by two main inputs, (i.e., the climbing fiber and mossy fiber-parallel fiber pathway) and activations of these inputs elicit characteristic effects in its Purkinje cells: that is, the so-called complex spikes and simple spikes. Target neurons of the Purkinje cells in the cerebellar nuclei show rebound firing, which has been implicated in the processing and storage of motor coordination signals. Yet, it is not known to what extent these rebound ph ...[more]