Associations between cognitive, functional, and FDG-PET measures of decline in AD and MCI.
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ABSTRACT:
SUBMITTER: Landau SM
PROVIDER: S-EPMC2891865 | biostudies-literature | 2011 Jul
REPOSITORIES: biostudies-literature
Publications
Associations between cognitive, functional, and FDG-PET measures of decline in AD and MCI.
Landau Susan M SM Harvey Danielle D Madison Cindee M CM Koeppe Robert A RA Reiman Eric M EM Foster Norman L NL Weiner Michael W MW Jagust William J WJ
Neurobiology of aging 20090805 7
The Functional Activities Questionnaire (FAQ) and Alzheimer's Disease Assessment Scale-cognitive subscale (ADAS-cog) are frequently used indices of cognitive decline in Alzheimer's disease (AD). The goal of this study was to compare FDG-PET and clinical measurements in a large sample of elderly subjects with memory disturbance. We examined relationships between glucose metabolism in FDG-PET regions of interest (FDG-ROIs), and ADAS-cog and FAQ scores in AD and mild cognitive impairment (MCI) pati ...[more]
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