Ontology highlight
ABSTRACT:
SUBMITTER: Kagami S
PROVIDER: S-EPMC2892169 | biostudies-literature | 2010 May
REPOSITORIES: biostudies-literature
Kagami Shinji S Rizzo Heather L HL Lee Jennifer J JJ Koguchi Yoshinobu Y Blauvelt Andrew A
The Journal of investigative dermatology 20091224 5
Th17, Th22, and Th1 cells are detected in psoriatic skin lesions and implicated in psoriasis pathogenesis, but inflammatory T cell numbers in blood, as well as the relative importance of each cell type, is unclear. Using 7-color flow cytometry, circulating Th17, Th22, and Th1 cells were quantified in 21 untreated psoriatics and 17 healthy individuals. CCR6 was the best cell surface marker for IL-17A+ cells when compared with IL-23R or CD161. CCR6+, IL-17A+, IL-22+, CCR6+IL-17A+, CCR6+IL-22+, CCR ...[more]