Ontology highlight
ABSTRACT:
SUBMITTER: Mazurek MP
PROVIDER: S-EPMC2892322 | biostudies-literature | 2010 Jun
REPOSITORIES: biostudies-literature
Mazurek Maciej P MP Prasad Puttur D PD Gopal Elangovan E Fraser Scott P SP Bolt Leszek L Rizaner Nahit N Palmer Christopher P CP Foster Christopher S CS Palmieri Ferdinando F Ganapathy Vadivel V Stühmer Walter W Djamgoz Mustafa B A MB Mycielska Maria E ME
EMBO reports 20100507 6
The prostate is a highly specialized mammalian organ that produces and releases large amounts of citrate. However, the citrate release mechanism is not known. Here, we present the results of molecular cloning of a citrate transporter from human normal prostate epithelial PNT2-C2 cells shown previously to express such a mechanism. By using rapid amplification of cDNA ends PCR, we determined that the prostatic carrier is an isoform of the mitochondrial transporter SLC25A1 with a different first ex ...[more]