Ontology highlight
ABSTRACT:
SUBMITTER: Clauson CL
PROVIDER: S-EPMC2893249 | biostudies-literature | 2010 Jul
REPOSITORIES: biostudies-literature
Clauson Cheryl L CL Saxowsky Tina T TT Doetsch Paul W PW
DNA repair 20100511 7
The DNA of all organisms is constantly damaged by exogenous and endogenous agents. Base excision repair (BER) is important for the removal of several non-bulky lesions from the DNA, however not much is known about the contributions of other DNA repair pathways to the processing of non-bulky lesions. Here we utilized a luciferase reporter system to assess the contributions of transcription-coupled repair (TCR), BER and nucleotide excision repair (NER) to the repair of two non-bulky lesions, 8-oxo ...[more]