Ontology highlight
ABSTRACT:
SUBMITTER: Wang B
PROVIDER: S-EPMC2893454 | biostudies-literature | 2010
REPOSITORIES: biostudies-literature
Wang Bo B Xu Yong-Fei YF He Bang-Shun BS Pan Yu-Qin YQ Zhang Li-Rong LR Zhu Chan C Qu Li-Li LL Wang Shu-Kui SK
Journal of experimental & clinical cancer research : CR 20100603
<h4>Background</h4>CD147 is a widely distributed cell surface glycoprotein that belongs to the Ig superfamily. CD147 has been implicated in numerous physiological and pathological activities. Enriched on the surface of many tumor cells, CD147 promotes tumor growth, invasion, metastasis and angiogenesis and confers resistance to some chemotherapeutic drugs. In this study, we investigated the possible role of CD147 in the progression of gastric cancer.<h4>Methods</h4>Short hairpin RNA (shRNA) expr ...[more]