TFM-Explorer: mining cis-regulatory regions in genomes.
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ABSTRACT:
SUBMITTER: Tonon L
PROVIDER: S-EPMC2896114 | biostudies-literature | 2010 Jul
REPOSITORIES: biostudies-literature
Publications
TFM-Explorer: mining cis-regulatory regions in genomes.
Tonon Laurie L Touzet Hélène H Varré Jean-Stéphane JS
Nucleic acids research 20100603 Web Server issue
DNA-binding transcription factors (TFs) play a central role in transcription regulation, and computational approaches that help in elucidating complex mechanisms governing this basic biological process are of great use. In this perspective, we present the TFM-Explorer web server that is a toolbox to identify putative TF binding sites within a set of upstream regulatory sequences of genes sharing some regulatory mechanisms. TFM-Explorer finds local regions showing overrepresentation of binding si ...[more]
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