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GlycoViewer: a tool for visual summary and comparative analysis of the glycome.


ABSTRACT: The GlycoViewer (http://www.systemsbiology.org.au/glycoviewer) is a web-based tool that can visualize, summarize and compare sets of glycan structures. Its input is a group of glycan structures; these can be entered as a list in IUPAC format or via a sugar structure builder. Its output is a detailed graphic, which summarizes all salient features of the glycans according to the shapes of the core structures, the nature and length of any chains, and the types of terminal epitopes. The tool can summarize up to hundreds of structures in a single figure. This allows unique, high-level views to be generated of glycans from one protein, from a cell, a tissue or a whole organism. Use of the tool is illustrated in the analysis of normal and disease-associated glycans from the human glycoproteome.

SUBMITTER: Joshi HJ 

PROVIDER: S-EPMC2896138 | biostudies-literature | 2010 Jul

REPOSITORIES: biostudies-literature

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GlycoViewer: a tool for visual summary and comparative analysis of the glycome.

Joshi Hiren J HJ   von der Lieth Claus-Wilhelm CW   Packer Nicolle H NH   Wilkins Marc R MR  

Nucleic acids research 20100525 Web Server issue


The GlycoViewer (http://www.systemsbiology.org.au/glycoviewer) is a web-based tool that can visualize, summarize and compare sets of glycan structures. Its input is a group of glycan structures; these can be entered as a list in IUPAC format or via a sugar structure builder. Its output is a detailed graphic, which summarizes all salient features of the glycans according to the shapes of the core structures, the nature and length of any chains, and the types of terminal epitopes. The tool can sum  ...[more]

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