Ontology highlight
ABSTRACT:
SUBMITTER: Potestio R
PROVIDER: S-EPMC2896196 | biostudies-literature | 2010 Jul
REPOSITORIES: biostudies-literature
Potestio R R Aleksiev T T Pontiggia F F Cozzini S S Micheletti C C
Nucleic acids research 20100505 Web Server issue
The ALADYN web server aligns pairs of protein structures by comparing their internal dynamics and detecting regions that sustain similar large-scale movements. The latter often accompany functional conformational changes in proteins and enzymes. The ALADYN dynamics-based alignment can therefore highlight functionally-oriented correspondences that could be more elusive to sequence- or structure-based comparisons. The ALADYN server takes the structure files of the two proteins as input. The optima ...[more]