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Antifungal susceptibility profile of human-pathogenic species of Lichtheimia.


ABSTRACT: Forty-four isolates belonging to human pathogenic species of Lichtheimia were tested against nine antifungal agents by using the EUCAST methodology. No remarkable differences were found between the clinical species, although L. ramosa showed slightly higher MICs for all drugs. Amphotericin B was the most active drug. Among azole drugs, posaconazole had the best activity in vitro and voriconazole was inactive. Echinocandins showed activity for some isolates, suggesting a potential role in combination therapy.

SUBMITTER: Alastruey-Izquierdo A 

PROVIDER: S-EPMC2897292 | biostudies-literature | 2010 Jul

REPOSITORIES: biostudies-literature

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Antifungal susceptibility profile of human-pathogenic species of Lichtheimia.

Alastruey-Izquierdo Ana A   Cuesta Isabel I   Walther Grit G   Cuenca-Estrella Manuel M   Rodriguez-Tudela Juan Luis JL  

Antimicrobial agents and chemotherapy 20100426 7


Forty-four isolates belonging to human pathogenic species of Lichtheimia were tested against nine antifungal agents by using the EUCAST methodology. No remarkable differences were found between the clinical species, although L. ramosa showed slightly higher MICs for all drugs. Amphotericin B was the most active drug. Among azole drugs, posaconazole had the best activity in vitro and voriconazole was inactive. Echinocandins showed activity for some isolates, suggesting a potential role in combina  ...[more]

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