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Evaluation of a commercial microarray system for detection of SHV-, TEM-, CTX-M-, and KPC-type beta-lactamase genes in Gram-negative isolates.

ABSTRACT: We evaluated the ability of a commercial microarray system (Check KPC/ESBL; Check-Points Health BV) to detect clinically important class A beta-lactamase genes. A total of 106 Gram-negative strains were tested. The following sensitivity and specificity results were recorded, respectively: for bla(SHV), 98.8% and 100%; for bla(TEM), 100% and 96.4%; and for bla(CTX-M) and bla(KPC), 100% and 100%.

SUBMITTER: Endimiani A

PROVIDER: S-EPMC2897517 | biostudies-literature | 2010 Jul

REPOSITORIES: biostudies-literature

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Evaluation of a commercial microarray system for detection of SHV-, TEM-, CTX-M-, and KPC-type beta-lactamase genes in Gram-negative isolates.

Endimiani Andrea A Hujer Andrea M AM Hujer Kristine M KM Gatta Julian A JA Schriver Andrew C AC Jacobs Michael R MR Rice Louis B LB Bonomo Robert A RA

Journal of clinical microbiology 20100526 7

We evaluated the ability of a commercial microarray system (Check KPC/ESBL; Check-Points Health BV) to detect clinically important class A beta-lactamase genes. A total of 106 Gram-negative strains were tested. The following sensitivity and specificity results were recorded, respectively: for bla(SHV), 98.8% and 100%; for bla(TEM), 100% and 96.4%; and for bla(CTX-M) and bla(KPC), 100% and 100%. ...[more]

PMID: 20504993

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