Ontology highlight
ABSTRACT:
SUBMITTER: Flesher DL
PROVIDER: S-EPMC2897739 | biostudies-literature | 2010 May
REPOSITORIES: biostudies-literature
Expert review of clinical immunology 20100501 3
Systemic lupus erythematosus (SLE) is a systemic autoimmune disease characterized by the production of antinuclear autoantibodies and the inflammatory infiltration of many organ systems. SLE is a complex disorder in which multiple genetic variants, together with environmental and hormonal factors, contribute to disease risk. In this article, we summarize our current understanding of the genetic contribution to SLE in light of recent genome-wide association studies, which have brought the total n ...[more]