Ontology highlight
ABSTRACT:
SUBMITTER: Shirai R
PROVIDER: S-EPMC2898406 | biostudies-literature | 2010 Jul
REPOSITORIES: biostudies-literature
Shirai Ryoichi R Gotou Rikiya R Hirano Fumiyasu F Ikeda Kiyoshi K Inoue Seiji S
The Journal of biological chemistry 20100504 28
Beta-type phospholipase A(2) inhibitory protein (PLIbeta) from the serum of the venomous snake Gloydius brevicaudus neutralizes basic phospholipase A(2) (PLA(2)) from its own venom, and it has 33% sequence homology with human leucine-rich alpha(2)-glycoprotein (LRG), which has been recently reported to bind cytochrome c (Cyt c) (Cummings, C., Walder, J., Treeful, A., and Jemmerson, R. (2006) Apoptosis 11, 1121-1129). In the present study, PLIbeta was found to bind Cyt c. The interactions of LRG ...[more]