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Targeting ketone drugs towards transport by the intestinal peptide transporter, PepT1.

ABSTRACT: Thiodipeptide prodrugs of the ketone nabumetone are shown to have affinity for, and be transported by, PepT1 in vitro.

SUBMITTER: Foley D 

PROVIDER: S-EPMC2898646 | biostudies-literature | 2009 Mar

REPOSITORIES: biostudies-literature

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Targeting ketone drugs towards transport by the intestinal peptide transporter, PepT1.

Foley David D   Bailey Patrick P   Pieri Myrtani M   Meredith David D  

Organic & biomolecular chemistry 20090121 6

Thiodipeptide prodrugs of the ketone nabumetone are shown to have affinity for, and be transported by, PepT1 in vitro. ...[more]

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