Double dissociation of two cognitive control networks in patients with focal brain lesions.
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ABSTRACT:
SUBMITTER: Nomura EM
PROVIDER: S-EPMC2900657 | biostudies-literature | 2010 Jun
REPOSITORIES: biostudies-literature
Publications
Double dissociation of two cognitive control networks in patients with focal brain lesions.
Nomura Emi M EM Gratton Caterina C Visser Renee M RM Kayser Andrew A Perez Fernando F D'Esposito Mark M
Proceedings of the National Academy of Sciences of the United States of America 20100614 26
Neuroimaging studies of cognitive control have identified two distinct networks with dissociable resting state connectivity patterns. This study, in patients with heterogeneous damage to these networks, demonstrates network independence through a double dissociation of lesion location on two different measures of network integrity: functional correlations among network nodes and within-node graph theory network properties. The degree of network damage correlates with a decrease in functional con ...[more]
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