Ontology highlight
ABSTRACT:
SUBMITTER: Drescher KM
PROVIDER: S-EPMC2901607 | biostudies-literature | 2010
REPOSITORIES: biostudies-literature
Drescher Kristen M KM Sharma Poonam P Lynch Henry T HT
Clinical & developmental immunology 20100610
High levels of microsatellite instability (MSI-high) are a cardinal feature of colorectal tumors from patients with Lynch Syndrome. Other key characteristics of Lynch Syndrome are that these patients experience fewer metastases and have enhanced survival when compared to patients diagnosed with microsatellite stable (MSS) colorectal cancer. Many of the characteristics associated with Lynch Syndrome including enhanced survival are also observed in patients with sporadic MSI-high colorectal cancer ...[more]