Freely suspended cellular "backpacks" lead to cell aggregate self-assembly.
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ABSTRACT:
SUBMITTER: Swiston AJ
PROVIDER: S-EPMC2903013 | biostudies-literature | 2010 Jul
REPOSITORIES: biostudies-literature
Publications
Freely suspended cellular "backpacks" lead to cell aggregate self-assembly.
Swiston Albert J AJ Gilbert Jonathan B JB Irvine Darrell J DJ Cohen Robert E RE Rubner Michael F MF
Biomacromolecules 20100701 7
Cellular "backpacks" are a new type of anisotropic, nanoscale thickness microparticle that may be attached to the surface of living cells creating a "bio-hybrid" material. Previous work has shown that these backpacks do not impair cell viability or native functions such as migration in a B and T cell line, respectively. In the current work, we show that backpacks, when added to a cell suspension, assemble cells into aggregates of reproducible size. We investigate the efficiency of backpack-cell ...[more]
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