Ontology highlight
ABSTRACT:
SUBMITTER: Sun Y
PROVIDER: S-EPMC2903145 | biostudies-literature | 2010 Apr
REPOSITORIES: biostudies-literature
Sun Y Y Feng Y Y Zhang C Q CQ Chen S B SB Cheng X G XG
International orthopaedics 20090512 4
Platelet-rich plasma (PRP), a platelet concentrate made of autogenous blood, has been used to improve bone and soft tissue defect healing in recent years. The aim of this study was to assess the effect of PRP on articular cartilage defects in a rabbit model. Forty-eight osteochondral defects created in the femoropatellar groove were (a) left untreated, (b) treated with autogenous PRP in a poly-lactic-glycolic acid (PLGA), or (c) with PLGA alone. Platelets were enriched 5.12-fold compared to norm ...[more]