Ontology highlight
ABSTRACT:
SUBMITTER: Hao MX
PROVIDER: S-EPMC2903792 | biostudies-literature | 2010 Aug
REPOSITORIES: biostudies-literature
Hao Ming-xiu MX Jiang Li-sheng LS Fang Ning-yuan NY Pu Jun J Hu Liu-hua LH Shen Ling-Hong LH Song Wei W He Ben B
Journal of lipid research 20100320 8
The endocannabinoid system has recently been attracted interest for its anti-inflammatory and anti-oxidative properties. In this study, we investigated the role of the endocannabinoid system in regulating the oxidized low-density lipoprotein (oxLDL)-induced inflammatory response in macrophages. RAW264.7 mouse macrophages and peritoneal macrophages isolated from Sprague-Dawley (SD) rats were exposed to oxLDL with or without the synthetic cannabinoid WIN55,212-2. To assess the inflammatory respons ...[more]