Ontology highlight
ABSTRACT:
SUBMITTER: Sun B
PROVIDER: S-EPMC2904038 | biostudies-literature | 2010 Aug
REPOSITORIES: biostudies-literature
The American journal of clinical nutrition 20100602 2
<h4>Background</h4>Beta(2)-adrenergic receptor (beta2-AR) is a susceptibility locus for hypertension, and polymorphisms at this site relate to salt sensitivity and low plasma renin activity (PRA). The Dietary Approaches to Stop Hypertension (DASH) dietary pattern lowers blood pressure and appears to interact with the renin-angiotensin-aldosterone system (RAAS).<h4>Objective</h4>We hypothesized that the DASH diet associates with increased RAAS activity, and genotype status at beta2-AR G46A modifi ...[more]