Ontology highlight
ABSTRACT:
SUBMITTER: Workman P
PROVIDER: S-EPMC2905514 | biostudies-literature | 2010 Jun
REPOSITORIES: biostudies-literature
Chemistry & biology 20100601 6
Chemical probes for interrogating biological processes are of considerable current interest. Cell permeable small molecule tools have a major role in facilitating the functional annotation of the human genome, understanding both physiological and pathological processes, and validating new molecular targets. To be valuable, chemical tools must satisfy necessary criteria and recent publications have suggested objective guidelines for what makes a useful chemical probe. Although recognizing that su ...[more]