Ontology highlight
ABSTRACT:
SUBMITTER: Jacobs NS
PROVIDER: S-EPMC2905525 | biostudies-literature | 2010 Jul
REPOSITORIES: biostudies-literature
Journal of neuroscience methods 20100513 2
Fear conditioning has become an indispensable behavioral task in an increasingly vast array of research disciplines. Yet one unresolved issue is how conditional fear to an explicit cue interacts with and is potentially confounded by fear prior to tone presentation, referred to as baseline fear. After tone-shock pairings, we experimentally manipulated baseline fear by presenting unpaired shocks in the testing chamber and then analyzed the accuracy of common methods for reporting tone fear. Our fi ...[more]