Ontology highlight
ABSTRACT:
SUBMITTER: Sanchez-Navarro I
PROVIDER: S-EPMC2906483 | biostudies-literature | 2010
REPOSITORIES: biostudies-literature
Sánchez-Navarro Iker I Gámez-Pozo Angelo A Pinto Alvaro A Hardisson David D Madero Rosario R López Rocío R San José Belén B Zamora Pilar P Redondo Andrés A Feliu Jaime J Cejas Paloma P González Barón Manuel M Angel Fresno Vara Juan J Espinosa Enrique E
BMC cancer 20100628
<h4>Background</h4>Gene expression profiling may improve prognostic accuracy in patients with early breast cancer. Our objective was to demonstrate that it is possible to develop a simple molecular signature to predict distant relapse.<h4>Methods</h4>We included 153 patients with stage I-II hormonal receptor-positive breast cancer. RNA was isolated from formalin-fixed paraffin-embedded samples and qRT-PCR amplification of 83 genes was performed with gene expression assays. The genes we analyzed ...[more]