Ontology highlight
ABSTRACT:
SUBMITTER: Yin C
PROVIDER: S-EPMC2908152 | biostudies-literature | 2010 Jun
REPOSITORIES: biostudies-literature
Yin Chunyue C Kikuchi Kazu K Hochgreb Tatiana T Poss Kenneth D KD Stainier Didier Y R DY
Developmental cell 20100601 6
Extracellular matrix (ECM) remodeling is critical for organogenesis, yet its molecular regulation is poorly understood. In zebrafish, asymmetric migration of the epithelial lateral plate mesoderm (LPM) displaces the gut leftward, allowing correct placement of the liver and pancreas. To observe LPM migration at cellular resolution, we transgenically expressed EGFP under the control of the regulatory sequences of the bHLH transcription factor gene hand2. We found that laminin is distributed along ...[more]