Ontology highlight
ABSTRACT:
SUBMITTER: Aguilar-Yanez JM
PROVIDER: S-EPMC2908544 | biostudies-literature | 2010 Jul
REPOSITORIES: biostudies-literature
Aguilar-Yáñez José M JM Portillo-Lara Roberto R Mendoza-Ochoa Gonzalo I GI García-Echauri Sergio A SA López-Pacheco Felipe F Bulnes-Abundis David D Salgado-Gallegos Johari J Lara-Mayorga Itzel M IM Webb-Vargas Yenny Y León-Angel Felipe O FO Rivero-Aranda Ramón E RE Oropeza-Almazán Yuriana Y Ruiz-Palacios Guillermo M GM Zertuche-Guerra Manuel I MI DuBois Rebecca M RM White Stephen W SW Schultz-Cherry Stacey S Russell Charles J CJ Alvarez Mario M MM
PloS one 20100722 7
<h4>Background</h4>The A/H1N1/2009 influenza pandemic made evident the need for faster and higher-yield methods for the production of influenza vaccines. Platforms based on virus culture in mammalian or insect cells are currently under investigation. Alternatively, expression of fragments of the hemagglutinin (HA) protein in prokaryotic systems can potentially be the most efficacious strategy for the manufacture of large quantities of influenza vaccine in a short period of time. Despite experime ...[more]