Ontology highlight
ABSTRACT:
SUBMITTER: Santos RL
PROVIDER: S-EPMC2909094 | biostudies-literature | 2006 Aug
REPOSITORIES: biostudies-literature
Santos Regie Lyn P RL Hassan Muhammad Jawad MJ Sikandar Shaheen S Lee Kwanghyuk K Lee Kwanghyuk K Ali Ghazanfar G Martin Protacio E PE Wambangco Michael Angelo L MA Ahmad Wasim W Leal Suzanne M SM
Human genetics 20060516 1
From a large collection of families with autosomal recessive non-syndromic hearing impairment (NSHI) from Pakistan, linkage has been established for two unrelated consanguineous families to 19p13.2. This new locus was assigned the name DFNB68. A 10 cM genome scan and additional fine mapping were carried out using microsatellite marker loci. Linkage was established for both families to DFNB68 with maximum multipoint LOD scores of 4.8 and 4.6. The overlap of the homozygous regions between the two ...[more]