Ontology highlight
ABSTRACT:
SUBMITTER: Lu X
PROVIDER: S-EPMC2909572 | biostudies-literature | 2010 Aug
REPOSITORIES: biostudies-literature
Lu Xuemei X Shapiro Joshua A JA Ting Chau-Ti CT Li Yan Y Li Chunyan C Xu Jin J Huang Huanwei H Cheng Ya-Jen YJ Greenberg Anthony J AJ Li Shou-Hsien SH Wu Mao-Lien ML Shen Yang Y Wu Chung-I CI
Genome research 20100528 8
Postmating reproductive isolation is often manifested as hybrid male sterility, for which X-linked genes are overrepresented (the so-called large X effect). In contrast, X-linked genes are significantly under-represented among testis-expressing genes. This seeming contradiction may be germane to the X:autosome imbalance hypothesis on hybrid sterility, in which the X-linked effect is mediated mainly through the misexpression of autosomal genes. In this study, we compared gene expression in fertil ...[more]