Ontology highlight
ABSTRACT:
SUBMITTER: Landmann F
PROVIDER: S-EPMC2910707 | biostudies-literature | 2010
REPOSITORIES: biostudies-literature
Landmann Frédéric F Foster Jeremy M JM Slatko Barton B Sullivan William W
PLoS neglected tropical diseases 20100727 7
Wolbachia are required for filarial nematode survival and fertility and contribute to the immune responses associated with human filarial diseases. Here we developed whole-mount immunofluorescence techniques to characterize Wolbachia somatic and germline transmission patterns and tissue distribution in Brugia malayi, a nematode responsible for lymphatic filariasis. In the initial embryonic divisions, Wolbachia segregate asymmetrically such that they occupy only a small subset of cells in the dev ...[more]