Neural dynamics of in vitro cortical networks reflects experienced temporal patterns.
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ABSTRACT:
SUBMITTER: Johnson HA
PROVIDER: S-EPMC2910842 | biostudies-literature | 2010 Aug
REPOSITORIES: biostudies-literature
Publications
Neural dynamics of in vitro cortical networks reflects experienced temporal patterns.
Johnson Hope A HA Goel Anubhuthi A Buonomano Dean V DV
Nature neuroscience 20100613 8
Learning ultimately relies on changes in the flow of activity in neural microcircuits. The plasticity of neural dynamics is particularly relevant for the processing of temporal information. Chronic stimulation of cultured rat cortical networks revealed experience-dependent plasticity in neural dynamics. We observed changes in the temporal structure of activity that reflected the intervals used during training, suggesting that cortical circuits are inherently capable of temporal processing on sho ...[more]
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