Ontology highlight
ABSTRACT:
SUBMITTER: Tungsiripat M
PROVIDER: S-EPMC2913151 | biostudies-literature | 2010 Jul
REPOSITORIES: biostudies-literature
Tungsiripat Marisa M Kitch Douglas D Glesby Marshall J MJ Gupta Samir K SK Mellors John W JW Moran Laura L Jones Lynne L Alston-Smith Beverly B Rooney James F JF Aberg Judith A JA
AIDS (London, England) 20100701 11
Several studies have reported improvement in lipids after antiretroviral therapy switches to tenofovir disoproxil fumarate (TDF)-containing regimens. We assessed lipid-lowering effects of TDF by adding it to a stable antiretroviral therapy regimen in this double-blind, placebo-controlled crossover study. We demonstrated that nonhigh-density lipoprotein cholesterol, low-density lipoprotein cholestrol, and total cholestrol improved significantly over TDF vs. placebo treatment in HIV-infected indiv ...[more]