Ontology highlight
ABSTRACT:
SUBMITTER: Glasheen BM
PROVIDER: S-EPMC2914218 | biostudies-literature | 2010 Aug
REPOSITORIES: biostudies-literature
Glasheen Bernadette M BM Robbins Renée M RM Piette Caitlin C Beitel Greg J GJ Page-McCaw Andrea A
Developmental biology 20100601 2
Organ size typically increases dramatically during juvenile growth. This growth presents a fundamental tension, as organs need resiliency to resist stresses while still maintaining plasticity to accommodate growth. The extracellular matrix (ECM) is central to providing resiliency, but how ECM is remodeled to accommodate growth is poorly understood. We investigated remodeling of Drosophila respiratory tubes (tracheae) that elongate continually during larval growth, despite being lined with a rigi ...[more]