Ontology highlight
ABSTRACT:
SUBMITTER: Zhao DM
PROVIDER: S-EPMC2915322 | biostudies-literature | 2007 Dec
REPOSITORIES: biostudies-literature
Acta crystallographica. Section E, Structure reports online 20071212 Pt 1
The title chiral compound, C(13)H(14)N(2)O(4), was prepared by an intra-cyclization reaction of methyl (S)-1-(4-hydr-oxy-5-meth-oxy-2-nitro-benz-yl)-5-oxopyrrolidine-2-carboxyl-ate in the presence of ethanol and iron. The five-membered substituted pyrrole ring adopts an approximate envelope conformation, while the seven-membered substituted diazepine ring displays a twist-boat conformation. Inter-molecular O-H⋯O and N-H⋯O hydrogen bonding helps to stabilize the crystal structure. ...[more]