Ontology highlight
ABSTRACT:
SUBMITTER: Novik V
PROVIDER: S-EPMC2916286 | biostudies-literature | 2010 Aug
REPOSITORIES: biostudies-literature
Novik Veronica V Hofreuter Dirk D Galán Jorge E JE
Infection and immunity 20100601 8
Campylobacter jejuni is the leading cause of infectious gastroenteritis in industrialized nations. Its ability to enter and survive within nonphagocytic cells is thought to be very important for pathogenesis. However, little is known about the C. jejuni determinants that mediate these processes. Through an extensive transposon mutagenesis screen, we have identified several loci that are required for C. jejuni efficient entry and survival within epithelial cells. Among these loci, insertional mut ...[more]