Ontology highlight
ABSTRACT:
SUBMITTER: Corredor V
PROVIDER: S-EPMC2916335 | biostudies-literature | 2010 Aug
REPOSITORIES: biostudies-literature
Corredor Vladimir V Murillo Claribel C Echeverry Diego F DF Benavides Julie J Pearce Richard J RJ Roper Cally C Guerra Angela P AP Osorio Lyda L
Antimicrobial agents and chemotherapy 20100524 8
The therapeutic efficacy of sulfadoxine-pyrimethamine (SP) in treating uncomplicated Plasmodium falciparum malaria is unevenly distributed in Colombia. The Andes mountain range separates regions in the west where malaria is endemic from those in the east and constitutes a barrier against gene flow and the dispersal of parasite populations. The distribution of dhfr and dhps genotypes of 146 P. falciparum samples from the eastern Amazon and Orinoco basins and Northwest and Southwest Pacific region ...[more]