Ontology highlight
ABSTRACT:
SUBMITTER: Olsson-Carter K
PROVIDER: S-EPMC2916846 | biostudies-literature | 2010 Aug
REPOSITORIES: biostudies-literature
Olsson-Carter Katherine K Slack Frank J FJ
PLoS genetics 20100805 8
To form functional neuronal connections, axon outgrowth and guidance must be tightly regulated across space as well as time. While a number of genes and pathways have been shown to control spatial features of axon development, very little is known about the in vivo mechanisms that direct the timing of axon initiation and elongation. The Caenorhabditis elegans hermaphrodite specific motor neurons (HSNs) extend a single axon ventrally and then anteriorly during the L4 larval stage. Here we show th ...[more]