Ontology highlight
ABSTRACT:
SUBMITTER: Kim JW
PROVIDER: S-EPMC2917478 | biostudies-literature | 2010 Aug
REPOSITORIES: biostudies-literature
Kim Joseph W JW Amin A R M Ruhul AR Shin Dong M DM
Cancer prevention research (Philadelphia, Pa.) 20100727 8
Recently, squamous cell carcinoma of the head and neck chemoprevention research has made major advances with novel clinical trial designs suited for the purpose, use of biomarkers to identify high-risk patients, and the emergence of numerous molecularly targeted agents and natural dietary compounds. Among many natural compounds, green tea polyphenols, particularly (-)-epigallocatechin-3-gallate (EGCG), possess remarkable potential as chemopreventive agents. EGCG modulates several key molecular s ...[more]