Cellular and molecular mechanisms of bone remodeling.
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ABSTRACT:
SUBMITTER: Raggatt LJ
PROVIDER: S-EPMC2919071 | biostudies-literature | 2010 Aug
REPOSITORIES: biostudies-literature
Publications
Cellular and molecular mechanisms of bone remodeling.
Raggatt Liza J LJ Partridge Nicola C NC
The Journal of biological chemistry 20100525 33
Physiological bone remodeling is a highly coordinated process responsible for bone resorption and formation and is necessary to repair damaged bone and to maintain mineral homeostasis. In addition to the traditional bone cells (osteoclasts, osteoblasts, and osteocytes) that are necessary for bone remodeling, several immune cells have also been implicated in bone disease. This minireview discusses physiological bone remodeling, outlining the traditional bone biology dogma in light of emerging ost ...[more]
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