Ontology highlight
ABSTRACT:
SUBMITTER: Ton-Hoang B
PROVIDER: S-EPMC2919506 | biostudies-literature | 2010 Aug
REPOSITORIES: biostudies-literature
Cell 20100801 3
DNA transposition has contributed significantly to evolution of eukaryotes and prokaryotes. Insertion sequences (ISs) are the simplest prokaryotic transposons and are divided into families on the basis of their organization and transposition mechanism. Here, we describe a link between transposition of IS608 and ISDra2, both members of the IS200/IS605 family, which uses obligatory single-stranded DNA intermediates, and the host replication fork. Replication direction through the IS plays a crucia ...[more]