Ontology highlight
ABSTRACT:
SUBMITTER: Govin J
PROVIDER: S-EPMC2919718 | biostudies-literature | 2010 Aug
REPOSITORIES: biostudies-literature
Govin Jérôme J Schug Jonathan J Krishnamoorthy Thanuja T Dorsey Jean J Khochbin Saadi S Berger Shelley L SL
Nucleic acids research 20100407 14
We previously showed that histone H4 serine-1 phosphorylation (H4S1ph) is evolutionarily conserved during gametogenesis, and contributes to post-meiotic nuclear compaction and to full completion of sporulation in the yeast Saccharomyces cerevisiae. Previous studies showed that H4S1ph and another modification of the same histone, H4 acetylation (H4ac), do not occur together and have opposing roles during DNA double-strand break (DSB) repair. In this study, we investigated the relationship between ...[more]