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Development of the ATAQ-IPF: a tool to assess quality of life in IPF.


ABSTRACT: There is no disease-specific instrument to assess health-related quality of life (HRQL) in patients with idiopathic pulmonary fibrosis (IPF).Patients' perspectives were collected to develop domains and items for an IPF-specific HRQL instrument. We used item variance and Rasch analysis to construct the ATAQ-IPF (A Tool to Assess Quality of life in IPF).The ATAQ-IPF version 1 is composed of 74 items comprising 13 domains. All items fit the Rasch model. Domains and the total instrument possess acceptable psychometric characteristics for a multidimensional questionnaire. The pattern of correlations between ATAQ-IPF scores and physiologic variables known to be important in IPF, along with significant differences in ATAQ-IPF scores between subjects using versus those not using supplemental oxygen, support its validity.Patient-centered and careful statistical methodologies were used to construct the ATAQ-IPF version 1, an IPF-specific HRQL instrument. Simple summation scoring is used to derive individual domain scores as well as a total score. Results support the validity of the ATAQ-IPF, and future studies will build on that validity.

SUBMITTER: Swigris JJ 

PROVIDER: S-EPMC2920246 | biostudies-literature | 2010 Jul

REPOSITORIES: biostudies-literature

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Development of the ATAQ-IPF: a tool to assess quality of life in IPF.

Swigris Jeffrey J JJ   Wilson Sandra R SR   Green Kathy E KE   Sprunger David B DB   Brown Kevin K KK   Wamboldt Frederick S FS  

Health and quality of life outcomes 20100731


<h4>Background</h4>There is no disease-specific instrument to assess health-related quality of life (HRQL) in patients with idiopathic pulmonary fibrosis (IPF).<h4>Methods</h4>Patients' perspectives were collected to develop domains and items for an IPF-specific HRQL instrument. We used item variance and Rasch analysis to construct the ATAQ-IPF (A Tool to Assess Quality of life in IPF).<h4>Results</h4>The ATAQ-IPF version 1 is composed of 74 items comprising 13 domains. All items fit the Rasch m  ...[more]

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