Ontology highlight
ABSTRACT:
SUBMITTER: Moller DV
PROVIDER: S-EPMC2920247 | biostudies-literature | 2010 Jul
REPOSITORIES: biostudies-literature
Møller Daniel V DV Pecini Redi R Gustafsson Finn F Hassager Christian C Hedley Paula P Jespersgaard Cathrine C Torp-Pedersen Christian C Christiansen Michael M Køber Lars V LV
BMC medical genetics 20100729
<h4>Background</h4>It is believed that hereditary hemochromatosis (HH) might play a role in cardiac disease (heart failure (HF) and ischemia). Mutations within several genes are HH-associated, the most common being the HFE gene. In a large cohort of HF patients, we sought to determine the etiological role and the prognostic significance of HFE genotypes.<h4>Methods</h4>We studied 667 HF patients (72.7% men) with depressed systolic function, enrolled in a multicentre trial with a follow-up period ...[more]