Ontology highlight
ABSTRACT:
SUBMITTER: Neklason DW
PROVIDER: S-EPMC2922112 | biostudies-literature | 2008 Oct
REPOSITORIES: biostudies-literature
Neklason Deborah W DW Thorpe Brett L BL Ferrandez Angel A Tumbapura Anil A Boucher Kenneth K Garibotti Gilda G Kerber Richard A RA Solomon Cindy H CH Samowitz Wade S WS Fang John C JC Mineau Geraldine P GP Leppert Mark F MF Burt Randall W RW Kuwada Scott K SK
The American journal of gastroenterology 20080730 10
<h4>Objectives</h4>Most colorectal cancers (CRCs) arise from adenomatous polyps, but the effects of CRC family history on adenoma risk are not well known. This issue is clinically relevant since several medical societies currently recommend earlier and more rigorous colorectal screening for individuals with a strong family history of CRC.<h4>Methods</h4>Colonoscopies were performed in 236 first-, second-, and third-degree relatives of 40 index CRC cases from six large kindreds selected from a la ...[more]