Ontology highlight
ABSTRACT:
SUBMITTER: Gautier A
PROVIDER: S-EPMC2923064 | biostudies-literature | 2010 Jun
REPOSITORIES: biostudies-literature
Nature structural & molecular biology 20100530 6
Seven-helix membrane proteins represent a challenge for structural biology. Here we report the first NMR structure determination of a detergent-solubilized seven-helix transmembrane (7TM) protein, the phototaxis receptor sensory rhodopsin II (pSRII) from Natronomonas pharaonis, as a proof of principle. The overall quality of the structure ensemble is good (backbone r.m.s. deviation of 0.48 A) and agrees well with previously determined X-ray structures. Furthermore, measurements in more native-li ...[more]