Ontology highlight
ABSTRACT:
SUBMITTER: Woo YH
PROVIDER: S-EPMC2923606 | biostudies-literature | 2010 Aug
REPOSITORIES: biostudies-literature
Woo Yong H YH Walker Michael M Churchill Gary A GA
PloS one 20100818 8
<h4>Background</h4>Gene order in eukaryotic genomes is not random. Genes showing similar expression (coexpression) patterns are often clustered along the genome. The goal of this study is to characterize coexpression clustering in mammalian genomes and to investigate the underlying mechanisms.<h4>Methodology/principal findings</h4>We detect clustering of coexpressed genes across multiple scales, from neighboring genes to chromosomal domains that span tens of megabases and, in some cases, entire ...[more]