Ontology highlight
ABSTRACT:
SUBMITTER: Bissler JJ
PROVIDER: S-EPMC2923715 | biostudies-literature | 2010 Oct
REPOSITORIES: biostudies-literature
Bissler John J JJ Siroky Brian J BJ Yin Hong H
Pediatric nephrology (Berlin, Germany) 20100121 10
Glomerulocystic disease is a rare renal cystic disease with a long descriptive history. Findings from recent studies have significantly advanced the pathophysiological understanding of the disease processes leading to this peculiar phenotype. Many genetic syndromes associated with glomerulocystic disease have had their respective proteins localized to primary cilia or centrosomes. Transcriptional control of renal developmental pathways is dysregulated in obstructive diseases that also lead to gl ...[more]