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ABSTRACT:
SUBMITTER: Coornaert A
PROVIDER: S-EPMC2925231 | biostudies-literature | 2010 Apr
REPOSITORIES: biostudies-literature
Coornaert Audrey A Lu Alisa A Mandin Pierre P Springer Mathias M Gottesman Susan S Guillier Maude M
Molecular microbiology 20100325 2
Numerous small RNAs regulators of gene expression exist in bacteria. A large class of them binds to the RNA chaperone Hfq and act by base pairing interactions with their target mRNA, thereby affecting their translation and/or stability. They often have multiple direct targets, some of which may be regulators themselves, and production of a single sRNA can therefore affect the expression of dozens of genes. We show in this study that the synthesis of the Escherichia coli pleiotropic PhoPQ two-com ...[more]