Ontology highlight
ABSTRACT:
SUBMITTER: Van Wagoner RM
PROVIDER: S-EPMC2928153 | biostudies-literature | 2008 Nov
REPOSITORIES: biostudies-literature
Van Wagoner Ryan M RM Deeds Jonathan R JR Satake Masayuki M Ribeiro Anthony A AA Place Allen R AR Wright Jeffrey L C JL
Tetrahedron letters 20081101 45
The karlotoxins (KmTxs) are a family of compounds produced by the dinoflagellate Karlodinium veneficum that cause membrane permeabilization. The structure of KmTx 1, determined using extensive 2D NMR spectroscopy, is very similar to the amphidinols and related compounds, though KmTx 1 features unique structural modifications of the conserved core region. The structure of KmTx 1 differs from that reported for KmTx 2, the only other reported karlotoxin to date, in lacking chlorination at its termi ...[more]