Ontology highlight
ABSTRACT:
SUBMITTER: Chaudhuri N
PROVIDER: S-EPMC2928610 | biostudies-literature | 2010 Aug
REPOSITORIES: biostudies-literature
Chaudhuri N N Paiva C C Donaldson K K Duffin R R Parker L C LC Sabroe I I
American journal of physiology. Lung cellular and molecular physiology 20100430 2
Induction of effective inflammation in the lung in response to environmental and microbial stimuli is dependent on cooperative signaling between leukocytes and lung tissue cells. We explored how these inflammatory networks are modulated by diesel exhaust particles (DEP) using cocultures of human monocytes with epithelial cells. Cocultures, or monoculture controls, were treated with DEP in the presence or absence of LPS or flagellin. Production of cytokines was explored by Western blotting and EL ...[more]